Qvirus Platform announced today the release of Adeno-Associated Virus Services with a comprehensive portfolio of products and services for the efficient design, development, manufacturing and analytical testing of AAV vector.

New York, USA - July 14, 2020 /MarketersMedia/ —

Qvirus Platform, a major branch of Creative Biogene, the global biotechnology products and services provider with the leading market position in gene research and discovery, announced today the release of Adeno-Associated Virus Services with a comprehensive portfolio of products and services for the efficient design, development, manufacturing and analytical testing of AAV vector.

As the key step in the development of AAV vectors is to discover that the prototype AAV2 vector genome can be cross-packed into the capsids of multiple different AAV isolates from multiple species. This process is called pseudo-serotyping and has been proven to have powerful functions that can impart novel tropism and biologicality to a single genome/capsid structure, and greatly improve the practicality and flexibility of the AAV vector system.

Recombinant AAV vector is currently one of the most commonly used viral vectors for gene therapy, cell therapy (generated by CRISPR genome editing and chimeric antigen receptor T (CAR T) knockout and knock-in cell lines)-cell engineering (using Lentivirus or lentivirus only for cell engineering), and academics study gene expression and silencing in mammalian systems through gene knock-in and knock-out. AAV is very suitable as a vector for gene transfer and a tool for genome editing because:

- Simple and easy to use;
-Transfer genes to dividing cells and non-dividing cells, and various tissue types from muscle to brain;
-Lack pathogenicity and only causes very low immunogenicity;
-Allow the protein to be expressed in the host cell for a long time.

For more than a decade, Creative Biogene has been optimizing the AAV production system, including the design and construction of AAV plasmid vectors and the preparation of low endotoxin plasmids, host cells for AAV packaging, cell culture media and AAV packaging process, small and large-scale AAV purification process. Members of the professional AAV production team have successfully produced high-titer, high-quality AAV from small to large for customers worldwide. In order to fulfill its role as a recombinant viral expression vector, the original wild-type AAV has been extensively modified to contain only the necessary genes required for viral packaging. The AAV capsid protein determines the tropism of the virus, and scientists have used this property to construct recombinant AAV targeting specific types of mammalian cells.

Creative Biogene’s complete customized adeno-associated virus (AAV) production services include: 1) AAV plasmid vector construction; 2) No auxiliary AAV packaging; 3) Purification of AAV; 4 ) AAV titration by qPCR.

“We are capable to propose expert consultation at all stages of the AAV project, in addition, our powerful tissue targeting, unique serotype and promoter combination guarantee the highest quality standards and purification options to meet your experimental needs.” said Marcia Brady, the marketing director of Creative Biogene, she also claimed, “Creative Biogene’s advanced technology can help customers reduce AAV production costs and deliver AAV in less than two months.”

About Creative Biogene Qvirus Platform
Qvirus Platform, as a division of Creative Biogene, providing world-class packaging services for a variety of virus vector products. The expertise and years of experience have made Qvirus platform become a well-recognized industry leader in supporting the development of gene therapy and scientists worldwide.

Contact Info:
Name: Marcia Brady
Email: Send Email
Organization: Creative Biogene
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
Phone: 631-619-7922
Website: https://qvirus.creative-biogene.com/

Source URL: https://marketersmedia.com/qvirus-platform-optimized-aav-service-platform-to-fulfill-the-needs-in-gene-expression-and-knockdown-experiments/88968482

Source: MarketersMedia

Release ID: 88968482